Samuel Lewis married (1) in 1803, Sarah Attaway Miller (1785-c1822), of Caroline Co., Va., and (2) Maria Turner Baylis [or Bayless] (c1806-62), in Morganfield, Ky. Ten children with his first wife were Judge George Washington (1804-79), Thomas Miller (1806-33)(unm.), Eliza Ariss (1809-34), John Bankhead (1810-78), Mary Willis (1812-86), Sarah Attaway (1814-71), LCDR Henry Howell (1817-93), Catherine Daingerfield (1820-49), Janette Gilson (c1825-), and Dr. William A.P. Lewis (1827-) who lived in Sacramento, Ca.

Samuel Lewis's father was Maj. George Lewis, fourth son of Col. Fielding (1725-81) and Betty Washington Lewis (1733-97), who was born in Fredericksburg, Va. He lived in Berryville, Va. and then 17 miles east of Fredericksburg at "Marmion" which is open to the public. He served in the Revolution, 1776-79, and in the Whiskey Rebellion in 1794. He inherited from George Washington 1300 acres on the Ohio and Great Kanawha Rivers. He married in 1779, Catherine Daingerfield (1764-1820), daughter of Col. William (c1740-81) and Mary Willis Daingerfield, of Coventry, Spotsylvania County, Va. Their children were Samuel (1780-1842); Mary Willis (1782-1834); and Daingerfield Lewis (1785-1862) who married in 1807, Lucy Brockenbrough Pratt (-1856). Mary Willis Lewis (1782-1834) married her cousin in 1800, Col. Byrd Charles Willis (1781-1846) and last lived at Pensacola, Fla. They had with other issue, Catherine Daingerfield Willis (1803-67) who married (1) Atcheson Gray (-c1822), and (2) in 1826, attorney Achille Murat (1801-47), eldest son of Joachim Murat (-1815), King of Naples and brother-in-law of Emp. Napoleon Bonaparte (1769-1821).

See See Albert Welles, The Pedigree and History of the Washington Family (New York, 1879), 177-178, 207-208; Merrow Egerton Sorley, Lewis of Warner Hall (Baltimore, 1935), 153-186; John B. Burke, Burke's Presidential Families of the United States (London, 1975), 51; Dr. Justin M. Glenn, The Washingtons, A Family History, Volume One, Seven Generations of the Presidential Branch (Savas Beatie, El Dorado Hills, Ca. 2014), I: 151; James Houston Barr III, Lt. Colonel Nathaniel Pope, c1610-1660, of Virginia, Ancestor of Washington, Governors and Legislators, History of His Descendants (Louisville, Ky. 2018), 20.