Physiology Researcher. Ernest Henry Starling received notoriety starting in the late 19th century as a British researcher. In 1890 he set the stage for the modern understanding of the origin of the lymph circulatory system and the microcirculatory forces regulating the partition of the extracellular fluid between plasma and the interstitial space, which causes edema. This would correlate with congested heart failure or dropsy as it was called in this era. Secondly, another subject of his research was hormones. He went to Germany twice, in 1885 and 1894, to study with other physiology researchers. In 1902 he was founder of the science of endocrinology. He demonstrated the existence of peristalsis, and coined the term “hormone” for the substance secreted by the pancreas, which stimulates the secretion of digestive juices. His third subject of research was the analysis of the heart's activity as a pump, which is known as the “Frank-Starling Law .” And last, he did research in 1924 on the function of the kidney, including evidence for the existence of the anti-diuretic hormone or vasopressin. Born the oldest in a family with seven children, his father was a lawyer for the Crown, who spent most of his time in India leaving his wife and children in England. He received his early education from 1872 to 1879 at Islington before entering King’s College School from 1880 to 1882. He had a classic education and learned to speak German. In 1882, he entered Guy’s Hospital Medical School in London, and received a Bachelor’s in Medicine Degree, graduating with honors in 1889. He then became a demonstrator in physiology at Guy’s Hospital and in 1890 began part-time work in Sir Edward Albert Sharpey-Schäfer’s laboratory at University College, where he began his collaborations with his brother-in-law, William Maddock Bayliss with the study of the heart and hormones. On December 21, 1891 he married a widow of one of his professors, Florence Amelia Wooldridge, daughter of Sir E. H. Sieveking, F.R.C.P. The couple had three daughters and a son plus a step-daughter from Amelia’s first marriage. Starling became an elected fellow of the Royal Society in 1899. With his acceptance in the same year of the Jodrell professorship at University College, Starling finally joined Bayliss fulltime in research and publishing papers together. During World War I, he researched poisonous gases as warfare. Disappointed that England was going to war with Germany. he openly spoke about his much respect for the Germans scientists. As a middle-aged medical officer, he had to take refresher courses before tending to the wounded as he had a successful career as a researcher not a bedside healer. After a frustrating episode with the military’s politics overriding his medical decisions and being deployed to an isolated Greek isle with no laboratory, he resigned his commission, returning to England without receiving any decoration for service. After seeing first-hand, the lack of learning the young soldiers had from public education, he was amazed and attempted to start reforms in the British public education system, but none of needed corrections happened in his lifetime. In 1913 he received the Royal Medal from the Royal Academy. In 1919 he delivered the most significant lecture of his career, correcting some of his earlier oversimplified statements on circulatory system, but the lecture was poorly attended and published in a less popular periodical. Today, this research is recognized as being a very important find. In 1922 Starling accepted the Royal Society’s Foulerton research professorship and traveled the world teaching. He died during a recreational sea voyage to the Caribbean. Traveling alone, he was found dead on the boat one morning, had no autopsy performed to document cause of death, and was buried in Half Way Tree, Kingston, Jamaica without any family present on a rainy day. He had been diagnosed in 1920 with colon cancer and half of his colon was surgically removed, which was a risky surgery in that time period. He had weakened over the last year but still active. With all his achievements, he was never knighted, but his brother-in-law was. He was nominated four times for a Nobel Prize but never received one, yet many others with equal achievements were honored. He was blunt when speaking about politics and often stepping on toes, which may have been the reason not receiving the recognition he deserved. He published numerous medical papers. Both his books, “Elements of Human Physiology” in 1892 and “Principles of Human Physiology “ in 1912, earned high praises as standard works: “Elements of Human Physiology” has had 32 editions with the last in 2016, where as “Principles of Human Physiology” has had 197 editions with the last in 2012 and in three languages. He published several other books with all being successful for years. Danish author, Jen H. Henriksen, has published his biography “Ernest Henry Starling” in 2020.